EstroQuench is a Hormone Specific Formulation of ingredients that have documented anti-aromatase activity as well as androgenic adaptogens which support the function of endogenous aromatase inhibitors. Collectively these herbs promote minimal production and function of estrogens, while promoting testosterone function, including optimal sexual function in both genders. This formulation is designed to quench excessive production of estrogens and aberrant functions of them while supporting optimal function of androgens by maintaining the health of androgen producing glands.†
Hormone Specific Formulation provided by Douglas Laboratories and formulated by Dr. Joseph J Collins is created to support the optimal function of specific hormones through the use of hormone specific adaptogens, hormone specific agonists and hormone specific functional mimetics. This formulation may be used as part of a hormone health program with dietary and nutrient support. In addition, this formulation may be used by clinicians as an adjuvant to support optimal hormone health in patients who have been prescribed bioidentical hormone therapies.
FUNCTIONS Aromatase (a cytochrome P450 enzyme {CYP19}) is the enzyme that controls the conversion of androgens to estrogens. More specifically, aromatase is the enzyme responsible for catalyzing the biosynthesis of androstenedione into estrone, and the biosynthesis of testosterone to estradiol. Estrogens include the broad range of aromatized hormones created form androgens. The specific attribute of estrogens that separate them from progestogens, androgens and corticoids is that estrogens are the only aromatized steroid hormones. Estradiol, the most potent endogenous estrogen, is biosynthesized by aromatization from androgens by aromatase (which is also called estrogen synthase). Both Males and females produce endogenous estrogen from testosterone via the enzyme aromatase. In aromatase inhibition, there is less conversion of testosterone and other androgens into estrogens. The end result is lower estrogen levels and higher androgen levels. Endogenous aromatase inhibition is recognized as a normal physiological process in human beings as well as other species. In humans, there are a number of naturally occurring, endogenous aromatase inhibitors. Endogenous means the substance is produced inside the organism – it is the opposite of exogenous aromatase inhibitors such as a prescription aromatase inhibitors. The primary functions of EstroQuench™ are to support the natural production and function of endogenous aromatase inhibitors, and to support the natural production of testosterone and other androgens to maintain adequate levels of the substrates of androgen metabolites, which acts as aromatase inhibitors. This is accomplished by supporting the function of testosterone producing glands in both gender, and by supporting the function of testosterone tissues through the use of herbs that mimic the actions of testosterone. The synergistic combination of specific herbs and flavanoids in EstroQuench™ support important functions associated with optimal estrogen health in both genders through anti-aromatase specific actions of these herbs which:
• Decrease estrogen dominance by supporting androgen production and supporting endogenous aromatase inhibitors.
• Support the production and the function of endogenous aromatase inhibitors. • Decrease the production of estrogens by inhibiting aromatase activity in both genders.
• Support optimal sexual function in both genders.
• Promote production of other androgens by adrenal glands in both genders.
• Mimic specific functions of testosterone metabolites, thereby acting as aromatase inhibitors and acting as testosterone functional agonists.
PHYTOTHERAPEUTIC ACTIONS The following is a list of the phytotherapeutic actions of th
